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- DOI 10.18231/j.achr.2025.018
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A rare case of primary choriocarcinoma of lung metastasizing to brain
Primary choriocarcinoma of the lung (PCC) is a rare and aggressive malignancy with a poor prognosis. A 24-year-old female presented with headaches and seizures. Brain MRI revealed a metastatic lesion, and biopsy showed trophoblastic tumor cells. Elevated Beta-HCG levels suggested gestational trophoblastic disease, but imaging ruled out uterine involvement. Chest CT revealed a lung mass, and biopsy confirmed PCC. The diagnosis was established based on the absence of a uterine primary and lung involvement. Despite surgery and chemotherapy, prognosis remains poor. This case highlights the importance of considering PCC in patients with metastatic disease and high Beta-HCG levels, emphasizing the need for thorough evaluation for accurate diagnosis and timely treatment.
Keywords: Choriocarcinoma, Lung, Human β-hCG, Brain
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How to Cite This Article
Vancouver
Agarwal L, Jain K, Agrawal M, Agarwal N. A rare case of primary choriocarcinoma of lung metastasizing to brain [Internet]. IP Arch Cytol Histopathol Res. 2025 [cited 2025 Oct 02];10(2):65-68. Available from: https://doi.org/10.18231/j.achr.2025.018
APA
Agarwal, L., Jain, K., Agrawal, M., Agarwal, N. (2025). A rare case of primary choriocarcinoma of lung metastasizing to brain. IP Arch Cytol Histopathol Res, 10(2), 65-68. https://doi.org/10.18231/j.achr.2025.018
MLA
Agarwal, Lakshmi, Jain, Kalpit, Agrawal, Manmohan, Agarwal, Nidhi. "A rare case of primary choriocarcinoma of lung metastasizing to brain." IP Arch Cytol Histopathol Res, vol. 10, no. 2, 2025, pp. 65-68. https://doi.org/10.18231/j.achr.2025.018
Chicago
Agarwal, L., Jain, K., Agrawal, M., Agarwal, N.. "A rare case of primary choriocarcinoma of lung metastasizing to brain." IP Arch Cytol Histopathol Res 10, no. 2 (2025): 65-68. https://doi.org/10.18231/j.achr.2025.018