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- DOI 10.18231/j.achr.2025.020
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CrossMark
Metastatic deposit of Alveolar rhabdomyosarcoma in cervical lymphadenopathy in a 23 year male patient: A case report
- Author Details:
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Shana Nikhat Khan
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Ranjana Hawaldar *
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Ekta Patidar
Shana Nikhat Khan
Ranjana Hawaldar *
Ekta Patidar
Cervical lymphadenopathy due to metastatic alveolar rhabdomyosarcoma (ARMS), presenting without a recognizable primary tumour, is a rare entity. We report a case of 23 year male patient diagnosed with fine needle aspiration, histopathology and IHC (Immunohistochemistry) markers for definitive diagnosis. The immunohistochemical analysis revealed intense positivity for myogenin and desmin, favouring the diagnosis of alveolar rhabdomyosarcoma.
Keywords: Rhabdomyosarcoma, Immunohistochemistry, Alveolar rhabdomyosarcoma.
References
- Parham DM, Garr FG. Alveolar rhabdomyosarcoma. In: Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F, editors. WHO Classification of Tumours of Soft Tissue and Bone. 4th ed. Lyon, France: IARC Press; 2013. p. 130–2
- Newton WA Jr, Soule EH, Hamoudi AB, Reiman HM, Shimada H, Beltangady M, et al. Histopathology of childhood sarcomas, 76 Khan et al. / IP Archives of Cytology and Histopathology Research 2025;10(2):72-76 Intergroup Rhabdomyosarcoma Studies I and II: clinicopathologic correlation. J Clin Oncol. 1988;6(1):67–75.
- Horn RC Jr, Enterline HT. Rhabdomyosarcoma: a clinicopathological study and classification of 39 cases. Cancer. 1958;11(1):181–99.
- Yadav SK, Sinha DK, Ahmed A, Azhar T, Sinha M. Primary Intra- Abdominal Rhabdomyosarcoma in an Adult: an Unusual Presentation and Review of Literature. Indian J Surg Oncol. 2015;6(2):119–22.
- WHO Classification of Tumours Editorial Board, editors. World Health Organization classification of tumours: soft tissue and bone tumours. 5th ed. Vol. 3. Lyon: IARC; 2020.
- Esnaola NF, Rubin BP, Baldini EH, Vasudevan N, Demetri GD, Fletcher CD, et al. Response to chemotherapy and predictors of survival in adult rhabdomyosarcoma. Ann Surg. 2001;234(2):215–
- Ferrari A, Dileo P, Casanova M, Bertulli R, Meazza C, Gandola L, et al. Rhabdomyosarcoma in adults. A retrospective analysis of 171 patients treated at a single institution. Cancer. 2003;98(3):571–80
- Mekni A, Bouraoui S, Boussen H, May A, Kchir N. Lymphadenopathic form of alveolar rhabdomyosarcoma: A case report. Tunis Med. 2004;82(2):241–4.
- Durán Padilla MA, Rodríguez Martínez HA, Chávez Mercado L, Soto Abraham MV, Ortega González P, Medina Cruz A. Atypical biological behavior of alveolar rhabdomyosarcoma in five patients. Rev Invest Clin. 1999;51(1):17–22.
- Barr FG. Soft tissue tumors: Alveolar rhabdomyosarcoma. Atlas Genet Cytogenet Oncol Haematol. 2009;13(12):981–5.