Endometrial histopathology in abnormal uterine bleeding

• Author Details:   
• B.G. Malathi
• Ashok. M

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Introduction: In routine practice abnormal uterine bleeding (AUB) is a distinct entity. In women of reproductive age with episodic unpredictable bleeding it is an indication of number of pathologic disorder. Histopathological assessment of endometrial curetting’s has high sensitivity.
 The present study was done in suspected AUB patients to evaluate histopathological patterns in endometrial biopsy among different age groups.
Methodology: A retrospective study done on 284 cases at tertiary teaching hospital, Karnataka. The study period was from Jan 2015 to April 2016. Clinical history and findings were collected and recorded. The histopathology study of endometrial patterns and age specific correlation was made.
Results: The majority of cases belonged to the age group of (41-50) years. The frequent histopathologic pattern was proliferative and secretory in (41.54% and 13.38% respectively). Endometrial hyperplasia in (34.50%) cases in fourth and fifth decades was the commonest pathology. Among these atypical hyperplasia constituted for ( 6.12%) cases. Endometrial carcinoma was diagnosed in (1.40%) cases in the post-menopausal age group .Chronic non-specific endometritis was noted in (2.11%) cases.
Conclusion: AUB has been reported to cause a significant impact on quality of women' s health ranging from infertility to premalignant and malignant changes in the endometrium. So evaluation of endometrial curettings would help to assess the functional status of endometrium for an effective planned treatment.

Keywords: Endometrium, Abnormal uterine bleeding, Menorrhagia, Histopathology.