IP Archives of Cytology and Histopathology Research
Official Publication of Khyati Education and Research Foundation
Official Publication of Khyati Education and Research Foundation
Print ISSN: 2581-5725
Online ISSN: 2456-9267
CODEN : IACHCL
IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...Original Article
Author Details :
Volume : 4, Issue : 4, Year : 2019
Article Page : 301-304
https://doi.org/10.18231/j.achr.2019.057
Abstract
Background: Leprosy is known to man since ancient times. Leprosy bacillus was discovered by
Gerhard Henrick Armauer Hansen in 1873. Ridley-Jopling classification takes into consideration clinical,
bacteriological, histopathological and immunological factor. The present study was done to correlate
clinical and histopathological diagnosis.
Materials and Methods : Fifty newly diagnosed cases of leprosy were included in the study during the
period from August 2011 to August 2013. H and E stained sections were observed for histopathological
features and classified according to Ridley & Jopling classification and a clinicopathological correlation
was made.
Result: Maximum numbers of cases diagnosed histopathologically belonged to borderline tuberculoid
18(36%) cases. Hundred percent correlation was seen between clinical diagnosis and histopathological
diagnosis in tuberculoid leprosy. The overall clinico-histopathological correlation in our study was 62%.
Conclusion: Histopathological classification is accurate as it considers immunologic response of the tissue,
whereas clinical classification considers only gross appearances of the lesions. Borderline leprosy cases are
in a continuous changing immunological spectrum and histopathologic classification identifies any recent
shift of a case in the spectrum.
Keywords: Histopathology, Leprosy, Ridley-Jopling’s classification.
How to cite : Balaji T G, Patil A M, Yendigeri S M, Clinical and histopathological correlation in leprosy: A two year prospective study. IP Arch Cytol Histopathol Res 2019;4(4):301-304
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