IP Archives of Cytology and Histopathology Research
Official Publication of Khyati Education and Research Foundation
Official Publication of Khyati Education and Research Foundation
Print ISSN: 2581-5725
Online ISSN: 2456-9267
CODEN : IACHCL
IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...Original Article
Author Details :
Volume : 5, Issue : 1, Year : 2020
Article Page : 70-74
https://doi.org/10.18231/j.achr.2020.014
Abstract
Introduction: Diseases affecting lymph nodes form a wide range of spectrum, from simple infection to
malignant pathology. A panel of IHC markers is decided based on morphologic differential diagnosis.
Aims and Objectives: To study the incidence of lymph nodal lesions with respect to age and sex and
their different histopathological patterns. To use Immunohistochemistry (IHC) for sub typing of neoplastic
lesions.
Materials and Methods: This study was done for a period of two and a half years in the Department
o f Pathology, from Jan 2017 to June 2019. All the specimens received were fixed in 10% formalin and
routinely processed and stained with Hematoxylin and Eosin (H&E.)
Results: A total of 230 lymph node biopsies were studied. Age distribution varied from 3 to 83 years
with female preponderance. Non – Neoplastic lesions were common comprising of 120 cases (52%)
while neoplastic lesions were 110 (48%). Among non neoplastic lesions reactive lymphadenitis (23%) was
common followed by tuberculous lymphadenitis (21%). In neoplastic lesions, metastatic diseases (20%)
predominated. IHC was done wherever necessary for subtyping of lymphomas and also to differentiate
lymphoma from carcinoma.
Conclusion: Lymph node biopsy with IHC plays an important role in establishing the cause for
lymphadenopathy and thus aids in therapy.
Keywords: Lymph node, Immunohistochemistry, Non-neoplastic, Neoplastic.
How to cite : Potti R, Inuganti V R, Chaitra B, Garima B, Durga Prasad B, Histopathological and immunohistochemical study of lymphnodal biopsies. IP Arch Cytol Histopathol Res 2020;5(1):70-74
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