IP Archives of Cytology and Histopathology Research
Official Publication of Khyati Education and Research Foundation
Official Publication of Khyati Education and Research Foundation
Print ISSN: 2581-5725
Online ISSN: 2456-9267
CODEN : IACHCL
IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...Original Article
Author Details :
Volume : 5, Issue : 2, Year : 2020
Article Page : 126-130
https://doi.org/10.18231/j.achr.2020.026
Abstract
Purpose/Objective: Breast cancer occurs in any of the cells of the mammary gland and exhibits a wide
scope of morphological features, different immunohistochemical profiles, and unique histopathological
subtypes that have specific clinical course and outcome. This study was conducted to assess various
histomorphological variants of breast carcinoma.
Material and Methods: Total of fifteen cases of modified radical mastectomy specimens were
prospectively assessed from January 2019 to June 2019 in pathology department of Dr B.R. Ambedkar
Medical college and hospital, Bangalore.
Observation: Out of 15 cases, Invasive ductal carcinoma NOS was most common variant accounting
for 10 cases (66.66%) followed by 1 cases of Invasive Lobular Carcinoma breast, 1 case of Invasive
micropapillary carcinoma, 1 case of Medullary carcinoma, 1 case of Metaplastic breast carcinoma. The
histological grading of breast carcinoma was done on the basis of Elston – Ellis modification of Scarff -
Bloom - Richardson grading system. We found that Grade 2 tumours were more common accounting to 9
cases (60%) followed by Grade 1 tumour (26.66%).
Conclusion: This study emphasizes on the importance of assessment of histopathological variants of breast
carcinoma in not only in establishing the final diagnosis, but also in predicting the prognosis by histological
typing, staging and grading of breast carcinoma.
Keywords: Breast carcinoma, MRM, Histomorphology, WHO, Staging, Grading.
How to cite : Manjunatha Y A, Jaishree T, Hugar N N, Chandrasekar N, Histomorphological evaluation of Breast carcinoma – A study of 15 cases. IP Arch Cytol Histopathol Res 2020;5(2):126-130
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