Print ISSN: 2581-5725
Online ISSN: 2456-9267
CODEN : IACHCL
IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...Original Article
Author Details :
Volume : 5, Issue : 3, Year : 2020
Article Page : 203-208
https://doi.org/10.18231/j.achr.2020.045
Abstract
Backgraound: Lymphadenopathy is a common clinical problem and biopsies done to know the cause of nodal enlargement may be neoplastic or non-neoplastic. Neoplastic lesions are mainly lymphohematogenous malignancies and metastases while non-neoplastic lymphadenopathies are varied. This study was undertaken to determine the histopathological spectrum of lymphadenectomies.
Materials and Methods: This was a descriptive study wherein 516 cases of histologically diagnosed peripheral lymph node biopsies from Aug 2016 to July 2019 were reviewed. Surgical resection specimens with lymph node dissection were excluded from the study.
Results: Neoplastic lesions were 47.68% (246 cases) consist of 21.5% (111 cases) of non-Hodgkin lymphoma, 17.6% (91 cases) of Hodgkin lymphoma and 8.5% (44 cases) of metastatic lesions. The nonneoplastic lesions were 52.32% (270 cases), which included 21.1% (109 cases) of tuberculosis followed by follicular hyperplasia, 9.5% (49 cases), chronic lymphadenitis 8.9% (46 cases).
Conclusions: Lymphoma was the most common cause of biopsied lymphadenopathy in our study (NHL comprising 21.5% and HL comprising 17.6%) followed by tubercular lymphadenitis (21.1%).
Keywords: Lymph Node, Non-neoplastic diseases, Hodgkin lymphoma, Non Hodgkin lymphoma.
How to cite : Amrita, Yadav V, Gupta M K, Kumar S, Descriptive analysis of histopathological diagnosis of lymph node biopsies at a Tertiary Referral Center. IP Arch Cytol Histopathol Res 2020;5(3):203-208
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