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To correlate cytological finding with clinical presentation and antithyroglobulin antibodies

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Original Article

Author Details : Dupinder Kaur*, Pooja Agarwal

Volume : 6, Issue : 2, Year : 2021

Article Page : 113-116

https://doi.org/10.18231/j.achr.2021.027

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Abstract

Background & Methods : All cases undergoing FNAC for thyroid swelling during study period were included in the study. The data was collected as per the pre-designed proforma including the general profile, clinical examination, laboratory investigations, USG findings and FNAC observations.
Result: In our study we found, correlation between antithyroglobulin antibody levels, 100-500 IU/ml (53), 501-1000 IU/ml (87) & >1000 IU/ml (10). Chi square = 8.2068; p-value= 0.7120 (insignificant). Correlation between T3 levels, Normal (18), Low (24) and High (108). Chi square = 12.3129; p-value= 0.3580 (insignificant). Correlation between T4 levels, Normal (00), Low (24) and High (108). Chi square = 19.9758; p-value= 0.00012 (significant). Correlation between T4 levels, Normal (00), Low (24) and High
(108). Chi square = 79.0167; p-value<0> Study Designed: Prospective Observational Study.
Conclusion: Antithyroglobulin antibodies may be insignificant statistically, yet they should always be tested for, in order to establish a better understanding of the cases. The ATG levels should be kept in mind before prescribing a treatment regime for such cases. This not only leads the pathologists to continuously seek for better than the present investigations but also leads clinicians to decide a dynamic management regime. Though there is a defined protocol for thyroid work up of clinically diagnosed patients, newer and more sensitive test need to be devised.

Keywords: Cytological, Clinical, Antithyroglobulin & Antibodies.

How to cite : Kaur D , Agarwal P , To correlate cytological finding with clinical presentation and antithyroglobulin antibodies. IP Arch Cytol Histopathol Res 2021;6(2):113-116

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