IP Archives of Cytology and Histopathology Research

Print ISSN: 2581-5725

Online ISSN: 2456-9267

CODEN : IACHCL

IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...

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Original Article


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32-41


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Ritika Gupta, Nikhil Sharma, Sarojini Raman*


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Cytohistological and immunohistochemical correlation of cutaneous neoplastic lesions: Three year retrospective study


Original Article

Author Details : Ritika Gupta, Nikhil Sharma, Sarojini Raman*

Volume : 7, Issue : 1, Year : 2022

Article Page : 32-41

https://doi.org/10.18231/j.achr.2022.007



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Abstract

Background: Neoplastic lesions in cutaneous and subcutaneous region comprise a large group of benign and malignant entities of different lineage. Clinical, morphological features and prognosis of these lesions differ a lot. For diagnosis FNAC (Fine needle aspiration cytology) is the first technicque applied followed by histology, immunohistochemisty (IHC) and so on.
Aim: Cytological evaluation of cutaneous and subcutaneous neoplasms and correlate with histopathology and IHC.
Settings and Design: Study of all palpable cutaneous and subcutaneous swellings presenting to cytology OPD (Out patient department) with further histopathological correlation in the three-year duration.
Materials and Methods : FNA cytosmears of the cases stained with leishman stain in most of cases. Histopathological and IHC correlation done in available cases.
Statistical Analysis : The data are expressed in descriptive statistics measures such as percentages and proportions.
Results: Out of 1032 total cases, most of the cases were benign (94.3%) with fewer malignant cases (5.7%). Lipomas 562(56.31 %) were the largest group among benign lesions followed by benign spindle cell lesions 286(28.65%). Metastatic (22, 64.7%) lesions were more in number than primary cutaneous malignancies (12,35.2%). Among adenocarcinomas, 4 metastatic cases (0.38%) from lung and breast each and among squamous cell carcinomas (SCC), 7(0.67%) primary SCC were seen. Biopsy correlation was available in 134(12.98%) cases and IHC done in 14(1.35%) cases.
Conclusion: Cutaneous neoplasms though benign in most of the cases, can be of critical aetiology with dismal prognosis. Hence they should not be taken lightly and diagnosed specifically with the help of imaging and cyohistological study whenever needed.
 

Keywords: Biopsy, Cytodiagnosis, Skin neoplasm


How to cite : Gupta R, Sharma N, Raman S, Cytohistological and immunohistochemical correlation of cutaneous neoplastic lesions: Three year retrospective study. IP Arch Cytol Histopathol Res 2022;7(1):32-41

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