IP Archives of Cytology and Histopathology Research

Print ISSN: 2581-5725

Online ISSN: 2456-9267

CODEN : IACHCL

IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...

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Original Article


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94-99


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Lalit Kumar, Nupur Kaushik, Rajdeep Singh, Harendra Kumar*, Ashish Gautum


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Study of various laboratory parameters in COVID-19 patients at a tertiary care center


Original Article

Author Details : Lalit Kumar, Nupur Kaushik, Rajdeep Singh, Harendra Kumar*, Ashish Gautum

Volume : 7, Issue : 2, Year : 2022

Article Page : 94-99

https://doi.org/10.18231/j.achr.2022.020



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Abstract

Introduction: In China, Wuhan City became the epicentre of unexplained cases of pneumonia in December 2019 and was temporarily labelled as, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). World Health Organization renamed it to coronavirus disease 2019 (COVID-19) in February 2020. In COVID-19 patients hematological profile showed increased total leukocyte count (TLC) and neutrophilic count, while decrease in other hematological parameters. The mild increase in TLC was found in severe disease patients; however significant increase was associated with clinical worsening and poor outcome. Significant elevation of various biochemical and inflammatory markers was noticed among COVID-19 patients
Materials and Methods: We conducted a retrospective study on RT-PCR confirmed 239 COVID-19 patients who were hospitalized in various COVID-19 facilities from Sept 2020 to Dec 2020. The laboratory data is used in de-identified form and doesn’t reveal identity of any subjects.
Results: A total of 239 cases were examined, out of which 176(73.7%) were male and 63(26.3%) were female (M:F ratio= 2.79:1). We found that 104 cases had Hb level ? 12gm/dl. We found that maximum patients (175) had TLC level >11000/cumm, 187 patients had ANC level > 7000/cumm. We found that 160 cases had serum urea of >43mg/dl, 134 case with serum creatinine of >1.4gm/dl.134 cases had ALT level of >40IU/L and 143 cases had AST levels of >42IU/L In this study out of 239 cases 126 cases were found to have increased level of all inflammatory markers levels.
Conclusion: We found a significant association of various inflammatory markers with haematological and biochemical parameters in COVID-19 patients.
 

Keywords: SARS­CoV­2 infection, Procalcitonin, Ferritin, D­dimer, Lactate dehydrogenase


How to cite : Kumar L, Kaushik N, Singh R, Kumar H, Gautum A, Study of various laboratory parameters in COVID-19 patients at a tertiary care center. IP Arch Cytol Histopathol Res 2022;7(2):94-99

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