IP Archives of Cytology and Histopathology Research
Official Publication of Khyati Education and Research Foundation
Official Publication of Khyati Education and Research Foundation
Print ISSN: 2581-5725
Online ISSN: 2456-9267
CODEN : IACHCL
IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...Original Article
Author Details :
Volume : 7, Issue : 2, Year : 2022
Article Page : 111-116
https://doi.org/10.18231/j.achr.2022.023
Abstract
Introduction: The cytological examination of serous effusions helps in diagnosis, staging and prognostication of patients with various malignancies. Combined analysis of Conventional smear and Cell block methods increases the diagnostic value of serous effusions.
Objectives: Of this study is to evaluate the cytomorphological features of ascitic and pleural fluids by the Conventional smear (CS) technique and the Cell block (CB) method, to compare them and also to assess the utility of their combined approach in the diagnosis of malignancy.
Materials and Methods: It is a cross sectional study, 110 specimens (64 ascitic and 46 pleural fluids) were subjected to evaluation by both CS and CB methods over a period of one year. Cellularity, architecture patterns, morphological features, nuclear & cytoplasmic details and also yield for malignancy were compared. Chi-square and p-value were calculated.
Results: Cell block method provided higher cellularity, better architectural patterns and additional yield for malignancy as compared to Conventional smear method. Chi square -19.0275, p- value is 0.000776. The p value is p<0>
Conclusion: The present study shows that it is advisable to routinely make CBs in every cases that were suspicious for malignancy by CS method.
Keywords: Pleural fluid, Ascitic fluid, Conventional Smear method, Cell Block method
How to cite : Devi J, Dhekial R, Kalita B, Cytomorphological evaluation of ascitic and pleural fluid with special reference to cell block method. IP Arch Cytol Histopathol Res 2022;7(2):111-116
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