IP Archives of Cytology and Histopathology Research
Official Publication of Khyati Education and Research Foundation
Official Publication of Khyati Education and Research Foundation
Print ISSN: 2581-5725
Online ISSN: 2456-9267
CODEN : IACHCL
IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...Case Report
Author Details :
Volume : 7, Issue : 2, Year : 2022
Article Page : 132-135
https://doi.org/10.18231/j.achr.2022.028
Abstract
Intramedullary spinal cord neoplasms are among one of the rare tumors and account for 4% to 10% of all the central nervous system tumors. Spinal cord ependymomas are the most common type of tumors in adults, and astrocytomas of the cord are most common in children. Among the ependymomas, Tanycytic type is a rare one that usually arises in the intramedullary part of the spine. The histology is unique which is emphasized by the absence of ependymal pattern of cells but has close resemblance to schwannoma and astrocytoma which poses a diagnostic challenge. Hereby we present a case of a young male diagnosed as tanycytic ependymoma but was initially thought to be a glioma clinically. The histology showed spindle cells with oval and elongated nuclei in fascicles in a fibrillary background suggesting a preliminary diagnosis of glioma / schwannoma. However with the help of Immunohistochemical staining, a strong immunoreactivity for glial fibrillary acidic protein (GFAP) with S-100 positivity, confirmed that the tumor was a tanycytic ependymoma. This case underlines the importance of accurate diagnosis of CNS tumors with the help of age, location, detailed histopathological examination and immunohistochemistry to differentiate from other neoplasms as treatment differs for different tumors.
Keywords: Tanycytic ependymoma, Intramedullary spinal cord tumor, GFAP
How to cite : Impana Bd, Seethalakshmi S, Jeris W, Raghavendran R, A challenging case of a tanycytic ependymoma – A case report. IP Arch Cytol Histopathol Res 2022;7(2):132-135
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