IP Archives of Cytology and Histopathology Research
Official Publication of Khyati Education and Research Foundation
Official Publication of Khyati Education and Research Foundation
Print ISSN: 2581-5725
Online ISSN: 2456-9267
CODEN : IACHCL
IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...Original Article
Author Details :
Volume : 7, Issue : 3, Year : 2022
Article Page : 164-170
https://doi.org/10.18231/j.achr.2022.036
Abstract
Introduction: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. It principally affects the cooler parts of the body, mainly skin and peripheral nerves; it also involves muscles, eyes, bones, testis and internal organs. Histopathological study of leprosy is very important in understanding the disease, its varied manifestations and complications. Clinical diagnosis of early leprosy lesions offer difficulties even to experienced dermatologists and leprologists. A definitive diagnosis may be possible by histopathological examination. Histological diagnosis when available is deemed the gold standard for diagnosis of leprosy.
Aims : To diagnose the case of leprosy using skin biopsy specimen. To study the clinical and histopathological correlation among leprosy patients attending a tertiary referral center. To classify the lesion according to Ridley and Jopling (RJ) classification.
Materials and Methods: The present study was conducted over a period of 18 months from Jan 2019 to July 2020. Total 51 new suspected cases were selected on clinical ground attending dermatological OPD. These patients were subjected to skin biopsy. Histopathological classification done on the basis of Riedly- Jopling criteria.
Out of total 51 cases 40 cases showing leprosy changes on histopathological examination.Majority of the patients were males (53.06%), while females (46.94%) constituted a minority with male to female ratio of 1.1:1.
Both clinically and histopathologically BT constituted the predominant group (62.7%) and (54.7%) respectively, followed by LL (15.6%).
Conclusion: Clinical diagnosis of early leprosy lesions offer difficulties even to experienced dermatologists and leprologists. A definitive diagnosis may be possible by histopathological & bacteriological examination.
Keywords: Leprosy, Clinicohistopathological correlation, Riedly Jopling Criterion
How to cite : Vishwanath S S, Rajput V, Rajput D, Wathore N, A study of clinico-histopathological correlation in leprosy. IP Arch Cytol Histopathol Res 2022;7(3):164-170
This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
