---

Reporting of Helicobacter pylori associated gastroduodenal diseases: A clinicopathological approach

---

Original Article

Author Details : Rishav Kumar Singh, Uttam Kumar Paul, Neha Mookim, Dipmala Das, Asitava Deb Roy*

Volume : 7, Issue : 4, Year : 2022

Article Page : 220-228

https://doi.org/10.18231/j.achr.2022.050

Suggest article by email

Get Permission

---

Abstract

Background: Helicobacter pylori is one of the most important causes of the varied spectrum of gastroduodenal diseases. It is important to have a collaborative approach between clinicians and pathologists for early initiation of treatment in patients and control the progression of the disease.
Aims: To evaluate the clinico-histopathological spectrum of gastroduodenal diseases with respect to Helicobacter pylori infection and provide recommendations for reporting and management of the same.
Materials and Methods: All patients of chronic dyspepsia not responding to conventional treatment were subjected to endoscopy, and mucosal biopsy samples were collected. A rapid urease test (RUT) and histopathology was performed on these samples. A histopathological evaluation was done with special reference to the Updated Sydney System for reporting of chronic gastritis.
Results: The specificity, sensitivity, positive predictive value, negative predictive value, and diagnostic accuracy of RUT were 97.22%, 94.04%, 98.75%, 87.5%, and 95%, respectively. The specificity, sensitivity, PPV, NPV and diagnostic accuracy of endoscopy were calculated as 98.68%, 88.5%, 95.83%, 96.15% and 96.07% respectively.
Conclusion: A clinicopathological approach for diagnosis of Helicobacter pylori associated gastroduodenal diseases which includes clinical assessment, endoscopic evaluation, RUT and histopathological analysis is of prime importance for effective management of such patients.

Keywords: Diagnosis, Helicobacter pylori, Histopathology, Endoscopy

How to cite : Singh R K, Paul U K, Mookim N, Das D, Roy A D, Reporting of Helicobacter pylori associated gastroduodenal diseases: A clinicopathological approach. IP Arch Cytol Histopathol Res 2022;7(4):220-228

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.