---

Cutaneous presentation in chediak – Higashi syndrome – A rare case report

---

Case Report

Author Details : Zebasultana Saiyed*, Shilpa Singh, Vardendra Kulkarni

Volume : 7, Issue : 4, Year : 2022

Article Page : 251-253

https://doi.org/10.18231/j.achr.2022.057

Suggest article by email

Get Permission

---

Abstract

A One and half year-old female child born out of 2consanguineous marriage came with multiple hypopigmented patches over the face, trunk and lower limbs. There was history of recurrent upper respiratory tract infections. On examination she had silvery grey hair, hypopigmented patches and mild hepatomegaly. Ophthalmological examination revealed oculocutaneous albinism. Skin biopsy showed coarse clumps of melanin pigment in the epidermis. Hair mount examination revealed melanin granules in cortex and medulla. Routine blood investigations were within normal limits. Peripheral smear examination showed giant granules in neutrophils and lymphocytes.
 

Keywords: Chediak­Higashi syndrome, Coarse clump melanin, Oculocutaneous albinism

How to cite : Saiyed Z, Singh S, Kulkarni V, Cutaneous presentation in chediak – Higashi syndrome – A rare case report. IP Arch Cytol Histopathol Res 2022;7(4):251-253

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.