IP Archives of Cytology and Histopathology Research
Official Publication of Khyati Education and Research Foundation
Official Publication of Khyati Education and Research Foundation
Print ISSN: 2581-5725
Online ISSN: 2456-9267
CODEN : IACHCL
IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...Original Article
Author Details :
Volume : 8, Issue : 1, Year : 2023
Article Page : 23-28
https://doi.org/10.18231/j.achr.2023.006
Abstract
Introduction: Coronaviruses had a wide range of symptoms from asymptomatic to severe illness and has caused significant morbidity and death among large population infected with this virus.
Aims and Objectives: To correlate CT severity score with each blood parameter like (TLC counts, Absolute neutrophil count, Absolute lymphocyte count, neutrophilic/lymphocytic ratio, quantitative D-dimer, ferritin, CRP, IL-6 and LDH). To assess diagnostic and prognostic significance of each parameter in predicting severity of disease.
Materials and Methods: The present study was a 1-year prospective, a hospital-based study from 1 August 2020 to 31 July 2021 and included 100, COVID-19 confirmed cases. The clinical, radiological and laboratory reports were collected. The CT score were compared with different blood parameters. The results were analyzed statistically using correlation coefficient(r).
Results and Observations: 27 patients having a CT severity score 1-10 were graded in mild category. 27 patients having CT severity score 11-15 were graded in moderate category.34 patients having CT severity score 16- 20 were graded as severe.12 patients having CT severity score 21-25 were graded as very severe. The present study showed raised TLC count > 11000 / µl in 35% patients suffering from COVID -19. Absolute neutrophil count > 7000/µl was seen in 50 % patients. 65% patients showed Absolute lymphocyte count <1000> 3.5 was seen in 83% patients. Raised D-Dimer >500 ng/ml was observed in 74 % patients. 92 % subjects showed raised Serum ferritin >150ng/ml. IL-6 >10pg/ml was seen in 92 % patients. Q-CRP >10 mg/l was seen in 97 % patients.
Conclusion: HRCT chest severity score of patients with COVID-19 has positive correlation with various laboratory parameters and hence can be used as an indicator of disease severity. It can play a vital role in the management of COVID-19 and should be used for comprehensive evaluation.
Keywords: COVID19, SARSCov2, ACE2, ANC, N/L ratio, LDH
How to cite : Meena R M, Saxena R, Agarwal L, Agarwal N, Singh S, A study on diagnostic and prognostic significance of laboratory parameters and its correlation with HRCT of lung in Covid-19 patients. IP Arch Cytol Histopathol Res 2023;8(1):23-28
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