Print ISSN: 2581-5725
Online ISSN: 2456-9267
CODEN : IACHCL
IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...Review Article
Author Details :
Volume : 8, Issue : 3, Year : 2023
Article Page : 151-155
https://doi.org/10.18231/j.achr.2023.036
Abstract
Lung cancer is the leading cause of cancer deaths globally with many new cases diagnosed each year. Recent studies have shown that an accumulation of various genetic abnormalities results in progressive morphologic changes in bronchial epithelium. Such changes are part of the continuum from precursor lesions to invasive lung cancers. Improvement in diagnostic modalities has made the detection of such preneoplastic lesions possible and resection at this stage confer excellent prognosis. The World Health Organization (WHO) has recognized atypical adenomatous hyperplasia/ adenocarcinoma in situ, squamous dysplasia/ squamous cell carcinoma in situ, and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia as the precursor lesions of adenocarcinoma, squamous cell carcinoma, and carcinoid tumors respectively. This review summarizes the key features of these preneoplastic lesions based on the current understanding and knowledge.
Keywords: Precursor lesions, Lung carcinoma, AAH, AIS, SCIS, DIPNECH
How to cite : Chakrabarti I, Mazumder S, Precursor lesions of lung tumors. IP Arch Cytol Histopathol Res 2023;8(3):151-155
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