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Spectrum of intestinal lesion: A clinicopathological study in a tertiary care centre

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Original Article

Author Details : Zoha Khan, Roobina Khan, Syeda Iqra Usman*, Nishat Afroz, Syed Hasan Harris

Volume : 8, Issue : 4, Year : 2023

Article Page : 236-240

https://doi.org/10.18231/j.achr.2023.053

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Abstract

Context: Intestine has wide spectrum of diseases comprising neoplastic and non-neoplastic lesions. Inflammatory bowel diseases are showing increasing trend and intestinal neoplasms are the most frequently observed and leading cause of death in India.
Objectives: This study aims to find the occurrence of various intestinal lesions, classify them as neoplastic and non-neoplastic and to correlate the histopathological findings with clinical profile of patient in tertiary care hospital of north India.
Materials and Methods: 1129 biopsies and resection specimens of intestinal lesions were examined over a period of two years. Sections were fixed, paraffin embedded and stained by H&E. Immunohistochemistry was applied wherever required.
Results: Nearly two third patients were males in their second decade who presented with abdominal pain as the most common complaint and majority were diagnosed with non-neoplastic diseases. Among non-neoplastic lesions non-specific inflammation was predominant in small intestine (47.04% cases) and appendicitis (55.0%) in large intestine. Adenocarcinoma was predominant in both small and large intestine with 80.77% and79.45% of neoplastic cases respectively.
Conclusion: This work gives a panoramic view of different intestinal pathologies and emphasises on the need of planning accurate diagnostic and screening strategies along with effective treatment plans both for neoplastic as well as non-neoplastic diseases.
 
Keywords: Intestinal Lesions, Neoplastic, Non­neoplastic

How to cite : Khan Z, Khan R, Usman S I, Afroz N, Harris S H, Spectrum of intestinal lesion: A clinicopathological study in a tertiary care centre. IP Arch Cytol Histopathol Res 2023;8(4):236-240

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