IP Archives of Cytology and Histopathology Research
Official Publication of Khyati Education and Research Foundation
Official Publication of Khyati Education and Research Foundation
Print ISSN: 2581-5725
Online ISSN: 2456-9267
CODEN : IACHCL
IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...Case Report
Author Details :
Volume : 9, Issue : 4, Year : 2024
Article Page : 209-209
https://doi.org/10.18231/j.achr.2024.048
Abstract
Leptomeningeal malignant melanoma is a rare disease in which tumor spreads to meninges surrounding brain and spinal cord. Here, we discuss a case of a47 year male who presented with complain of forgetfullness, difficulty in walking, urinary incontinence, drowsiness, unable to speak and with seizures. A CT brain showed hyperdense area and significant perilesional edema in right temporo-parital region which caused a mass effect. Subdural haemorrhage was noted in right parietal region with periventricular hypo density. For that, patient was operated for right side VP shunt and right frontotemporoparietal craniotomy with excision of right temporal space occupying lesion. HPE showed tumor to be composed of neoplastic cells arranged in sheets, nest and peritheliomatous pattern. Cells were epitheliod to spindly in nature. Mitosis were (>20/10 HPF). Cytoplasm of neoplastic cells showed melanin pigment.
Keywords: Malignant melanoma, Leptomeningeal melanomatosis, Melanocytes
How to cite : Rathod A M, Goyal A, Shaikh I, Mistry K, Leptomeningeal malignant melanoma - A rare case report. IP Arch Cytol Histopathol Res 2024;9(4):209-209
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