Print ISSN: 2581-5725
Online ISSN: 2456-9267
CODEN : IACHCL
IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...Original Article
Author Details :
Volume : 1, Issue : 2, Year : 2016
Article Page : 57-62
Abstract
Introduction: Interface dermatitis (ID) includes numerous skin dermatoses which have in common salient histopathological features but varied clinical presentation that have traditionally been referred to as the lichenoid tissue reaction/ID. The primary morphologic change is noted at the dermoepidermal junction with secondary susequent changes in the epidermis. The prototypic skin disease in this category is lichen planus (LP) and its variants. Several other inflammatory, infective and neoplastic conditions may show interface change.
Aim: The present study was planned to correlate the significance of Interface dermatitis with their clinico-pathological aspects.
Methodology: The material for the present retrospective study consisted of skin biopsy samples received from the outpatient department of dermatology. The study was done for a period of six years from 2009 to 2015.
Results: In the present study, a total of 54 cases were analysed which clinically presented as papulosquamous disorders. Majority of the cases were seen in women. On histopathological diagnosis majority were LP and its variants. The most consistent histolopathological feature noted was basal cell vacuolar degeneration in the epidermis along with a band of lymphocytic inflammatory infiltrate and pigment incontinence in the dermis. Clinicopathologic concordance was seen in 45 cases (83.33%) and discordance in 8 cases (14.81%).
Conclusion: Thus, combination of the histologic details, in correlation with the clinical data helps in arriving at a specific diagnosis of various ID.
Keywords: Clinicopathologic correlation, Interface dermatitis, Lichenoid tissue reaction, Papulosquamous disorders
How to cite : Malathi B, Sandhu J K, Interface dermatitis-Clinicopathologic Spectrum. IP Arch Cytol Histopathol Res 2016;1(2):57-62
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