Print ISSN: 2581-5725
Online ISSN: 2456-9267
CODEN : IACHCL
IP Archives of Cytology and Histopathology Research (ACHR) open access, peer-reviewed quarterly journal publishing since 2016 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing the article more...Original Article
Author Details :
Volume : 1, Issue : 2, Year : 2016
Article Page : 63-67
Abstract
Introduction: Chondroid syringoma also known as benign mixed tumor of the skin presents as a slow growing, painless dermal/subcutaneous nodule. The cytological features of this entity have been rarely described, and are limited to a few case reports. The present study emphasizes on the cytological features of chondroid syringoma on fine needle aspiration (FNA).
Materials and Methods: A retrospective analysis of all cases of chondroid syringoma diagnosed/missed on fine needle aspiration (FNA) with subsequent histopathologic confirmation over a period of five years (2011-2015) was undertaken. FNA was done using a 23 gauge needle fitted to a 10 mL syringe mounted on Franzen’s handle. Chondroid syringoma was diagnosed on cytology in 3 cases of which 2 were confined to head and neck region while 1 was in axilla. One case was misdiagnosed as fibroadenoma with secondary myxoid change on cytology.
Results: Case 1 was a 57-year-old man with a nodule in left axilla. Case 2 was a 52-year-old woman who presented with a nodule on tip of the nose. Case 3 was a 46-year-old man with nodule on upper lip. Case 4 was a 38-year-old lady with lump breast. FNA smears were cellular in all the cases and showed clusters of cells embedded in chondromyxoid stroma. Cells were round to oval with bland nuclear features and moderate amount of cytoplasm. Plentiful of chondromyxoid material was seen in the background. No cytological atypia/mitosis/necrosis was seen.
Conclusions: Chondroid syringoma can undoubtedly be diagnosed on FNA. Cytologic smears are reminiscent of pleomorphic adenoma of salivary gland. Rarity of this adnexal tumor may be responsible for the diagnosis being missed on evaluation of aspirates.
Keywords: Adnexal, Chondroid syringoma, Fine needle aspiration cytology
How to cite : Kundu R, Punia R S, Handa U, Dalal U, Chondroid syringoma: Cytomorphology of four cases and review of literature. IP Arch Cytol Histopathol Res 2016;1(2):63-67
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