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Histopathological study of distribution of non-neoplastic and neoplastic lesions in breast

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Original Article

Author Details : Nishita M Ghodasara*, Chetan Dharaiya, Jignasa Bhalodia

Volume : 4, Issue : 3, Year : 2019

Article Page : 259-264

https://doi.org/10.18231/j.achr.2019.048

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Abstract

Introduction: Breast carcinoma is no longer seen as a single disease but rather a multifaceted disease
comprised of distinct biological subtypes with varied natural history, presenting a diverse spectrum of
clinico-pathological and molecular features with different therapeutic and prognostic implications. The
present study was designed to evaluate the frequency, age, gender and histopathological features of breast
carcinoma.
Materials and Methods: All specimens of mastectomy, lumpectomy and tru cut biopsies for
histopathological examination were included except known case of malignancy and treated for malignancy.
It was a retrospective study conducted in the Department of Pathology, GMERS Medical college and Civil
Hospital, Sola, Ahmedabad from June 2017 to June 2019. The clinical details were recorded as per the
proforma. Tissue for H&E sections were fixed in 10% formalin and subjected to routine paraffin embedded
processing and stained with Hematoxylin and Eosin.
Results: Out of the total 230 cases of breast lesions, 113(49.13%) were diagnosed as benign neoplasm,
66 cases were malignant (28.69%) and 51 cases (22.18 %)were other non neoplastic conditions. Maximum
numbers of patients, 109 cases (47.39%) were between 11 - 30 years. Out of 66 malignant breast lesions,
53 were diagnosed as Infiltrative duct cell carcinoma (80.30 %), followed by malignant phylloides.
Conclusion: The pattern of breast lesions provides information about clinicopathological profile of breast
lesions. Histopathological diagnosis should be correlated with clinical diagnosis for patient’s betterment.

How to cite : Ghodasara N M, Dharaiya C, Bhalodia J, Histopathological study of distribution of non-neoplastic and neoplastic lesions in breast. IP Arch Cytol Histopathol Res 2019;4(3):259-264

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